null

NRF1 Rabbit Monoclonal Antibody (CAB3252)

SKU:
CAB3252
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NRF1 Rabbit Monoclonal Antibody
SKU:CAB3252
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 300-400 of human NRF1 (Q16656).
Sequence:LVPS QTVV QTFS NPDG TVSL IQVG TGAT VATL ADAS ELPT TVTV AQVN YSAV ADGE VEQN WATL QGGE MTIQ TTQA SEAT QAVA SLAE AAVA ASQE MQQG A
Tested Applications:WB IHC-P IP ChIP ELISA CUT&Tag
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μg
Synonyms:ALPHA-PAL; NRF1
Positive Sample:NIH/3T3,Mouse lung,Rat testis,HeLa,293T,HepG2
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:54kDa
Observed MW:68kDa

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.

Purification Method:Affinity purification
Gene ID:4899
Clone Number:ARC0768
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageCUT&Tag was performed using the CUT&Tag Assay Kit (pAG-Tn5) for Illumina(RK20265) from 10⁵ HepG2 cells with 1 μg NRF1 Rabbit mAb (CAB3252), along with a Goat Anti-Rabbit IgG(H+L). The CUT&Tag results indicate the enrichment pattern of NRF1 in representative gene loci (LINS1), as shown in figure.

Related Products