The NTHL1 Antibody (CAB6820) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By binding to the NTHL1 protein, researchers can accurately detect and analyze NTHL1 expression in various cell types.NTHL1 is crucial for repairing oxidative DNA damage and preventing mutations that can lead to cancer and other genetic disorders. Studies have shown that mutations in the NTHL1 gene are associated with an increased risk of developing certain cancers, making it a promising target for cancer research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
NTHL1 Antibody
SKU:
CAB6820
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FAP3, NTH1, OCTS3, hNTH1, NTHL1
Positive Sample:
A-549, HeLa, LO2, MCF-7
Cellular Localization:
Mitochondrion, Nucleus.
Calculated MW:
34kDa
Observed MW:
37kDa
The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
Purification Method
Affinity purification
Gene ID
4913
RRID
AB_2767396
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NTHL1 Rabbit pAb (CAB6820) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
