The NTMT1 Antibody (CAB7098) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human NTMT1 and has been validated for use in Western blot applications. By targeting the NTMT1 protein, researchers can study the role of methylation in cellular processes such as gene expression, signaling pathways, and protein function.NTMT1 plays a vital role in regulating the methylation of proteins, which in turn impacts various cellular processes, including DNA repair, cell cycle regulation, and gene transcription. Dysregulation of protein methylation has been implicated in diseases such as cancer, neurological disorders, and developmental abnormalities.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NTMT1 Antibody
SKU:
CAB7098
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
HeLa, SKOV3, U-87MG, A-431, Raji, Mouse brain, Rat ovary
Cellular Localization:
Nucleus.
Calculated MW:
25kDa
Observed MW:
25kDa
The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).
Purification Method
Affinity purification
Gene ID
28989
RRID
AB_2767653
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NTMT1 Rabbit pAb (CAB7098) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Immunofluorescence analysis of A-549 cells using NTMT1 Rabbit pAb (CAB7098). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
