The NUDT2 Antibody (CAB6868) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed in rabbits, demonstrates high reactivity towards human samples and is suitable for use in Western blotting applications. By binding specifically to the NUDT2 protein, this antibody allows for reliable detection and analysis in a variety of cell types, making it an excellent choice for investigations in biochemistry and molecular biology.NUDT2, also known as nudix hydrolase 2, plays a crucial role in maintaining cellular nucleotide pool balance and protecting cells from oxidative stress.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NUDT2 Antibody
SKU:
CAB6868
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
APAH1, IDDPN, NUDT2
Positive Sample:
SKOV3, HL-60, Mouse kidney, Mouse heart, Mouse brain, Mouse liver, Rat kidney, Rat heart
Cellular Localization:
Mitochondrial Matrix.
Calculated MW:
17kDa
Observed MW:
17kDa
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
Purification Method
Affinity purification
Gene ID
318
RRID
AB_2767429
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NUDT2 Rabbit pAb (CAB6868) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
