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Anti-ORM1 Antibody (CAB1799)

SKU:
CAB1799
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

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Antibody Name:Anti-ORM1 Antibody
Antibody SKU:CAB1799
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-201 of human ORM1 (NP_000598.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, Human serum, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-201 of human ORM1 (NP_000598.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TLDR ITGK WFYI ASAF RNEE YNKS VQEI QATF FYFT PNKT EDTI FLRE YQTR QDQC IYNT TYLN VQRE NGTI SRYV GGQE HFAH LLIL RDTK TYML AFDV NDEK NWGL SVYA DKPE TTKE QLGE FYEA LDCL RIPK SDVV YTDW KKDK CEPL EKQH EKER KQEE GES
Gene ID:5004
Uniprot:P02763
Cellular Location:Secreted
Calculated MW:23kDa
Observed MW:40kDa
Synonyms:ORM1, AGP-A, AGP1, HEL-S-153w, ORM
Background:This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.
UniProt Protein Function:ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: extracellular space; extracellular region

Molecular Function:protein binding

Biological Process: regulation of immune system process; transport; acute-phase response; inflammatory response

NCBI Summary:This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
UniProt Code:P02763
NCBI GenInfo Identifier:112877
NCBI Gene ID:5004
NCBI Accession:P02763.1
UniProt Secondary Accession:P02763,Q60590, P02764,
UniProt Related Accession:P02763
Molecular Weight:
NCBI Full Name:Alpha-1-acid glycoprotein 1
NCBI Synonym Full Names:orosomucoid 1
NCBI Official Symbol:ORM1  
NCBI Official Synonym Symbols:ORM; AGP1; AGP-A; HEL-S-153w  
NCBI Protein Information:alpha-1-acid glycoprotein 1
UniProt Protein Name:Alpha-1-acid glycoprotein 1
UniProt Synonym Protein Names:Orosomucoid-1; OMD 1
Protein Family:ORM1-like protein
UniProt Gene Name:ORM1  
UniProt Entry Name:A1AG1_HUMAN
Anti-ORM1 Antibody (CAB1799)Western blot analysis of extracts of various cell lines, using ORM1 antibody (CAB1799) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

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