The PARG Antibody (CAB10577) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is optimized for use in Western blot experiments and is known for its high affinity to human samples.PARG is a key player in the regulation of DNA damage response and is essential for maintaining genomic stability. Dysregulation of PARG activity has been implicated in various diseases, including cancer and neurodegenerative disorders. By targeting PARG with this antibody, researchers can investigate the role of PARG in DNA repair pathways and explore its potential as a therapeutic target in disease treatment.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
PARG Antibody
SKU:
CAB10577
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
8505
RRID
AB_2758119
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from PC-3 cells, using PARG Rabbit pAb (CAB10577) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
