The PAX4 Antibody (CAB5414) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically designed for use in detecting Pax4 in human samples and has been validated for Western blot applications.Pax4 is a transcription factor that is essential for the development and function of insulin-producing beta cells in the pancreas. Dysregulation of Pax4 has been linked to pancreatic disorders and diabetes, making it an important target for research in these areas.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
PAX4 Antibody
SKU:
CAB5414
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
KPD, MODY9, PAX4
Positive Sample:
Lovo
Cellular Localization:
Nucleus.
Calculated MW:
38kDa
Observed MW:
43kDa
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
Purification Method
Affinity purification
Gene ID
5078
RRID
AB_2766222
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Lovo cells, using PAX4 Rabbit pAb (CAB5414) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
