The PBXIP1 Antibody (CAB8790) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the PBXIP1 protein, this antibody allows for the detection and analysis of PBXIP1 levels in different cell types, making it an ideal choice for studies in cell biology and cancer research.PBXIP1 plays a critical role in cellular pathways that contribute to tumor development and progression, making it a potential target for therapeutic intervention in cancer treatment.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PBXIP1 Antibody
SKU:
CAB8790
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HPIP, PBXIP1
Positive Sample:
HeLa, LO2, BT-474, A-549
Cellular Localization:
Cytoplasm, Nucleus, Cytoskeleton.
Calculated MW:
81kDa
Observed MW:
110kDa
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.
Purification Method
Affinity purification
Gene ID
57326
RRID
AB_2770805
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PBXIP1 Rabbit pAb (CAB8790) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
