The PDCD6 Antibody (CAB6685) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to PDCD6, this antibody enables researchers to detect and analyze the protein in various cell types, making it an ideal choice for studies in cell biology and cancer research.PDCD6, also known as programmed cell death protein 6, is involved in regulating cell death and survival processes, making it a crucial target for understanding disease mechanisms and developing therapeutic interventions.
This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PDCD6 Antibody
SKU:
CAB6685
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Purification Method
Affinity purification
Gene ID
10016
RRID
AB_2767269
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from wild type(WT) and PDCD6 knockout (KO) 293T(KO) cells, using [KO Validated] PDCD6 Rabbit pAb (CAB6685) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunoprecipitation analysis of 200 μg extracts of HepG2 cells, using 3 μg PDCD6 antibody (CAB6685). Western blot was performed from the immunoprecipitate using PDCD6 antibody (CAB6685) at a dilution of 1:1000.
