100% Quality Guarantee
PhD-Level Technical Support
Key Features

PDK1/PDHK1 Monoclonal Antibody (CAB24749)

Datasheet MSDS
SKU CAB24749
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms PDK1, pyruvate dehydrogenase kinase 1, PDK1/PDHK1
$603

Request a formal quotation

A PDF quote with its own quote number, ready for your purchasing office to raise a PO against. Back within 4 working hours, from a PhD scientist — not an autoresponder.

  • PO-ready PDFQuote number, VAT, Incoterms
  • Volume pricing appliedDiscounts from 2 kits up
  • Valid 30 daysPrices held while you get sign-off
Anything we should know? optional

No account needed. We use your details only to prepare and send this quote. If it's urgent, say so in the box and we'll come back the same working day.
Global Shipping: 80+ Countries
White Glove Service: Available upon request
Batch Consistency: Contact Sales
Distributors: 60+ Countries
Contact Sales Quote or discount
Find Distributor 50+ countries
Technical Support PhD-level team
Live Chat Available now

Description

system_update_altDatasheetsystem_update_altMSDS

PDK1/PDHK1 Monoclonal Antibody (CAB24749)

The PDK1/PDHK1 Monoclonal Antibody (CAB24749) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, produced through hybridoma technology, specifically targets PDK1 and PDHK1 in human samples, providing accurate and reliable results in experiments such as Western blotting.PDK1 and PDHK1 are key enzymes involved in the regulation of glucose metabolism and the production of ATP in cells. Dysregulation of these proteins has been linked to various diseases, including cancer and metabolic disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:PDK1/PDHK1 Monoclonal Antibody
SKU:CAB24749
Size:100μL
Reactivity:Human, Mouse
Clone Number:ARC1355
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:Email for sequence
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PDK1, pyruvate dehydrogenase kinase 1, PDK1/PDHK1
Positive Sample:HeLa, Mouse brain
Cellular Localization:Mitochondrion Matrix.
Calculated MW:49kDa
Observed MW:49kDa

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Purification MethodAffinity purification
Gene ID5163
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PDK1/PDHK1 Rabbit mAb (CAB24749) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
View AllClose

0 Reviews

Write a Review
0
Based on 0 reviews

No reviews yet. Be the first to share your experience!

View AllClose

Related Products