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PE Anti-Human CD37 Antibody [IPO-24] (AGEL2832)

Datasheet MSDS
SKU AGEL2832
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone IPO-24
Conjugation PE
€94 - €357

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Description

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PE Anti-Human CD37 Antibody [IPO-24]

The CD37 Monoclonal Antibody (IPO-24) offered by AssayGenie is specifically designed for research involving the CD37 cell surface molecule. CD37 is known for its role in cell signaling and is a target for therapeutic antibodies in cancer treatments. This mouse monoclonal antibody, IPO-24, is highly specific for human CD37 and is validated for various applications, including flow cytometry and immunohistochemistry.CD37 is a crucial membrane protein involved in lymphocyte activation and proliferation, making it a key player in immune responses and cell cycle regulation. Research shows its potential as a therapeutic target in B-cell malignancies such as non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

The use of IPO-24 antibody enables the detection and analysis of CD37 expression in different cell types, providing valuable insights for immunology and oncology studies.By understanding the function and expression of CD37, researchers can further explore its role in disease pathology and develop targeted therapies that leverage its unique properties. The IPO-24 monoclonal antibody from AssayGenie offers researchers a reliable tool for investigating CD37 biology and its implications in cancer immunotherapy and other therapeutic approaches.

Product Title:PE Anti-Human CD37 Antibody [IPO-24]
SKU:AGEL2832
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IPO-24
Synonyms:Leukocyte antigen CD37;CD37;Tspan-26;TSPAN26;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11049
Gene ID:951
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD37 is a 40-52 kD type II transmembrane protein, also known as tetraspanin-26. It is a member of the transmembrane tetraspanin family. It can interact with integrins and other transmembrane 4 superfamily members (CD53, CD81, CD82). CD37 is expressed predominantly on B cells; low expression is detected on T cells and myeloid cells. No expression is reported on NK cells and plasma cells. It is involved in regulation of T cell proliferation.
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