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PE Anti-Human CD62L Antibody [HI62L]

The PE Anti-Human CD62L Antibody (HI62L) from AssayGenie is a cutting-edge tool designed for precise research involving CD62L, a crucial cell adhesion molecule known for its involvement in lymphocyte homing and activation. This antibody is meticulously produced to provide high specificity and sensitivity when detecting CD62L in human samples, making it an indispensable asset for immunologists and cancer researchers.CD62L, also referred to as L-selectin, serves as a key player in the immune response, facilitating the migration of lymphocytes to secondary lymphoid organs and sites of inflammation. By targeting CD62L, researchers can gain valuable insights into the mechanisms governing immune cell trafficking and activation, shedding light on various immunological processes.The PE Anti-Human CD62L Antibody (HI62L) is rigorously validated for flow cytometry applications, enabling precise quantification and characterization of CD62L-expressing cells in diverse cell populations.

Its exceptional performance and reliability make it an ideal choice for studies exploring immune cell dynamics, inflammatory responses, and the development of targeted therapies in conditions such as cancer and autoimmune disorders.Researchers and clinicians alike can rely on the PE Anti-Human CD62L Antibody (HI62L) from AssayGenie to enhance their understanding of CD62L biology and unravel the intricate workings of the immune system. Stay at the forefront of immunological research with this advanced antibody, driving innovation and discovery in the field of immune-mediated diseases and therapies.

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Product Title:	PE Anti-Human CD62L Antibody [HI62L]
SKU:	AGEL3485
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	HI62L
Synonyms:	L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG2a, κ
Isotype Control:	PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	PE
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P14151
Gene ID:	6402
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

PE Anti-Human CD62L Antibody [HI62L] (AGEL3485)

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