The CD81 Monoclonal Antibody (PE anti-human CD81 antibody 1.3.3.22) offered by AssayGenie is a valuable tool for research focusing on CD81, a key cell surface protein associated with various cellular functions. This antibody, generated specifically for human samples, is proven to be highly reactive in flow cytometry applications, allowing for the precise detection and analysis of CD81 expression in different cell populations.CD81, a member of the tetraspanin family, is involved in diverse biological processes such as cell adhesion, migration, and signaling. Its interaction with other proteins and its role in intracellular communication make it an intriguing target for investigation in fields like immunology, virology, and cancer research.
By using the CD81 Monoclonal Antibody, researchers can delve deeper into the mechanisms involving CD81 and uncover its implications in various physiological and pathological conditions.This antibody's specificity and reliability in detecting CD81 make it an essential tool for studies seeking to elucidate the functions and regulatory pathways associated with this protein. By gaining a better understanding of CD81's involvement in cellular processes, researchers can pave the way for the development of novel therapeutic strategies targeting diseases where CD81 plays a crucial role.
Product Title:
PE Anti-Human CD81 Antibody [1.3.3.22]
SKU:
AGEL2837
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
1.3.3.22
Synonyms:
CD81 antigen;CD81;26 kDa cell surface protein TAPA-1;Target of the antiproliferative antibody 1.Tetraspanin-28;Tspan-28;APA1; TSPAN28;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P60033
Gene ID:
975
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
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