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PE Anti-Mouse CD4 Antibody [RM4-5] (AGEL3488)

Datasheet MSDS
SKU AGEL3488
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone RM4-5
Conjugation PE
$50 - $116

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD4 Antibody [RM4-5]

The PE Anti-Mouse CD4 Antibody (RM4-5) is a valuable tool for researchers studying the CD4 protein, a crucial cell surface marker involved in immune system function. This antibody, specifically designed for use in flow cytometry applications, is raised in hamsters and exhibits high reactivity with mouse samples.CD4, a glycoprotein expressed on the surface of T helper cells, plays a key role in immune responses by interacting with major histocompatibility complex class II molecules. The PE Anti-Mouse CD4 Antibody (RM4-5) effectively binds to CD4, enabling accurate detection and quantification of CD4-expressing cells in various biological samples.

This makes it an essential reagent for investigating immune cell populations and studying immune responses in research settings.With its reliable performance and specificity for mouse CD4, this antibody is indispensable for immunology studies, including those focused on T cell biology, immune system regulation, and autoimmune diseases. Whether used for basic research or therapeutic development, the PE Anti-Mouse CD4 Antibody (RM4-5) offers a convenient and effective solution for scientists exploring the intricate mechanisms of the immune system.

Product Title:PE Anti-Mouse CD4 Antibody [RM4-5]
SKU:AGEL3488
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RM4-5
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;L3T4;T4;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P06332
Gene ID:12504
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.
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