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PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL3239)

Datasheet MSDS
SKU AGEL3239
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG1, k
Clone M/K-2.7
Conjugation PE/AF594
€125 - €313

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7]

The PE GenieFluor 594 Anti-Mouse CD106 Antibody (M/K-2.7) from AssayGenie (AGEL3239) is a high-quality antibody specifically designed for research involving mouse CD106, also known as VCAM-1. This antibody, optimized for flow cytometry applications, is generated using the M/K-2.7 hybridoma cell line and conjugated to PE GenieFluor 594 for easy detection and analysis.CD106 (VCAM-1) is a cell surface adhesion molecule that plays a crucial role in leukocyte recruitment during inflammation and immune responses. Its expression is induced by inflammatory cytokines and is involved in various physiological and pathological processes, including atherosclerosis, autoimmune diseases, and cancer metastasis.

The PE GenieFluor 594 Anti-Mouse CD106 Antibody is a valuable tool for investigating the expression and function of CD106 in different cell types and experimental settings.This antibody offers high sensitivity and specificity in detecting mouse CD106, making it an essential reagent for studies focusing on immune response modulation, inflammatory diseases, and cancer research. With its reliable performance and validated compatibility with flow cytometry techniques, the PE GenieFluor 594 Anti-Mouse CD106 Antibody (M/K-2.7) is a trusted solution for researchers aiming to explore the complex roles of CD106 in various biological contexts.

Product Title:PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL3239
Size:25µg, 100µg
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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