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PER1 Rabbit Polyclonal Antibody (CAB8449)

SKU:
CAB8449
Product Type:
Antibody
Applications:
WB
IHC
IF
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
  • Cell Biology Antibodies 12 Anti-PER1 Antibody CAB8449
  • Cell Biology Antibodies 12 Anti-PER1 Antibody CAB8449
  • Cell Biology Antibodies 12 Anti-PER1 Antibody CAB8449
  • Cell Biology Antibodies 12 Anti-PER1 Antibody CAB8449
  • Cell Biology Antibodies 12 Anti-PER1 Antibody CAB8449
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PER1 Rabbit Polyclonal Antibody
SKU:CAB8449
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2).
Sequence:MSGP LEGA DGGG DPRP GESF CPGG VPSP GPPQ HRPC PGPS LADD TDAN SNGS SGNE SNGH ESRG ASQR SSHS SSSG NGKD SALL ETTE SSKS TNSQ SPSP PSSS IAYS LLSA SSEQ DNPS TSGC SSEQ SARA RTQK ELMT ALRE LKLR LPPE RRGK GRSG TLAT LQYA LACV KQVQ ANQE YYQQ WSLE EGEP CSMD MSTY
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF,1:50 - 1:200
Synonyms:PER; hPER; RIGUI; PER1
Positive Sample:Mouse brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:136kDa
Observed MW:136kDa

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

Purification Method:Affinity purification
Gene ID:5187
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse brain, using PER1 Rabbit pAb (CAB8449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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