Anti-PER3 Antibody (CAB2219)
- SKU:
- CAB2219
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FASPS3
- GIG13
Frequently bought together:
Description
| Product Name: | PER3 Rabbit mAb |
| Product Code: | CAB2219 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | FASPS3, GIG13 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PER3 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse lung, Mouse kidney, Rat lung |
| Immunogen: | A synthesized peptide derived from human PER3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8863 |
| Uniprot: | P56645 |
| Calculated MW: | 132kDa |
| Observed MW: | 132kDa |
| UniProt Protein Function: | PER3: Component of the circadian clock mechanism which is essential for generating circadian rhythms. Can bind heme. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function Chromosomal Location of Human Ortholog: 1p36.23 Cellular Component: cytoplasm; nucleus Molecular Function: signal transducer activity; protein binding; ubiquitin protein ligase binding; kinase binding Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; signal transduction; regulation of circadian sleep/wake cycle, sleep |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014] |
| UniProt Code: | P56645 |
| NCBI GenInfo Identifier: | 317373535 |
| NCBI Gene ID: | 8863 |
| NCBI Accession: | P56645.4 |
| UniProt Secondary Accession: | P56645 |
| UniProt Related Accession: | P56645 |
| Molecular Weight: | |
| NCBI Full Name: | Period circadian protein homolog 3 |
| NCBI Synonym Full Names: | period circadian regulator 3 |
| NCBI Official Symbol: | PER3Â Â |
| NCBI Official Synonym Symbols: | GIG13; FASPS3Â Â |
| NCBI Protein Information: | period circadian protein homolog 3 |
| UniProt Protein Name: | Period circadian protein homolog 3 |
| UniProt Synonym Protein Names: | Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3 |
| Protein Family: | Period circadian protein |
| UniProt Gene Name: | PER3Â Â |
| UniProt Entry Name: | PER3_HUMAN |
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