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Anti-PIK3R4 Antibody (CAB15828)

SKU:
CAB15828
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 6 Anti-PIK3R4 Antibody CAB15828
  • Cell Biology Antibodies 6 Anti-PIK3R4 Antibody CAB15828
€139 - €419
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Description

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Antibody Name:Anti-PIK3R4 Antibody
Antibody SKU:CAB15828
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human PIK3R4 (NP_055417.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:Raji, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human PIK3R4 (NP_055417.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGNQ LAGI APSQ ILSV ESYF SDIH DFEY DKSL GSTR FFKV ARAK HREG LVVV KVFA IQDP TLPL TSYK QELE ELKI RLNS AQNC LPFQ KASE KASE KAAM LFRQ YVRD NLYD RIST RPFL NNIE KRWI AFQI LTAV DQAH KSGV RHGD IKTE NVMV TSWN WVLL TDFA SFKP TYLP EDNP ADFN YFFD TSRR RTCY IAPE RFVD GGMF ATEL EYMR DPST PLVD LNSN QRTR GELK RAMD IFSA GCVI AELF TEGV PLFD LSQL LAYR NGHF FPEQ VLNK IEDH SIRE LVTQ MIHR EPDK RLEA EDYL KQQR GNAF PEIF YTFL QPYM AQ
Gene ID:30849
Uniprot:Q99570
Cellular Location:Cytoplasmic vesicle, Late endosome, Lipid-anchor, Membrane, autophagosome
Calculated MW:153kDa
Observed MW:153kDa
Synonyms:PIK3R4, VPS15, p150
Background:
UniProt Protein Function:PIK3R4: Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
UniProt Protein Details:

Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, lipid; EC 2.7.11.1; Other group; VPS15 family

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: membrane; late endosome; nuclear pore; axoneme; cytosol

Molecular Function:protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity

Biological Process: macroautophagy; phospholipid metabolic process; late endosome to vacuole transport; toll-like receptor signaling pathway; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; innate immune response; protein targeting to vacuole; toll-like receptor 9 signaling pathway; peroxisome degradation; protein amino acid phosphorylation

UniProt Code:Q99570
NCBI GenInfo Identifier:74762700
NCBI Gene ID:30849
NCBI Accession:Q99570.3
UniProt Secondary Accession:Q99570,Q2TBF4,
UniProt Related Accession:Q99570
Molecular Weight:1358
NCBI Full Name:Phosphoinositide 3-kinase regulatory subunit 4
NCBI Synonym Full Names:phosphoinositide-3-kinase, regulatory subunit 4
NCBI Official Symbol:PIK3R4  
NCBI Official Synonym Symbols:p150; VPS15  
NCBI Protein Information:phosphoinositide 3-kinase regulatory subunit 4; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; phosphoinositide 3-kinase adaptor protein; phosphatidylinositol 3-kinase-associated p150; phosphoinositide-3-kinase, regulatory subunit 4, p150
UniProt Protein Name:Phosphoinositide 3-kinase regulatory subunit 4
UniProt Synonym Protein Names:PI3-kinase p150 subunit; Phosphoinositide 3-kinase adaptor protein
Protein Family:Phosphoinositide 3-kinase regulatory
UniProt Gene Name:PIK3R4  
UniProt Entry Name:PI3R4_HUMAN
Anti-PIK3R4 Antibody (CAB15828)Western blot analysis of extracts of various cell lines, using PIK3R4 antibody (CAB15828) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-PIK3R4 Antibody (CAB15828)Immunofluorescence analysis of NIH-3T3 cells using PIK3R4 Polyclonal Antibody (CAB15828) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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