Anti-PTGER2 Antibody (CAB9053)

SKU:
CAB9053
€129 - €349

Description

Technical Manual

Anti-PTGER2 Antibody

Product Name:Anti-PTGER2 Antibody
Product SKU:CAB9053
Size:20uL, 50 uL
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Background:

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]

Immunogen:A synthesized peptide derived from human PTGER2
Sequence:

Email for sequence

Gene ID:5732
Swiss Prot:P43116
Synonyms:EP2
Calculated MW:52kDa
Observed MW:52KDa
Reactivity:Human, Mouse, Rat
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Application Key:Western blotting Immunohistochemistry Immunofluorescence
Positive Samples:HeLa, A-549, THP-1, Mouse lung, Mouse liver, Mouse spleen, Rat testis
Cellular Location:

Product Images

Anti-PTGER2 Antibody (CAB9053)

Western blot - PTGER2 Rabbit mAb (CAB9053)

Uniprot Information

UniProt Protein Function:PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:prostaglandin E receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation; response to lipopolysaccharide; response to progesterone stimulus

Disease: Asthma, Nasal Polyps, And Aspirin Intolerance

NCBI Summary:This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]
UniProt Code:P43116
NCBI GenInfo Identifier:38258920
NCBI Gene ID:5732
NCBI Accession:P43116.2
UniProt Secondary Accession:P43116,Q52LG8, D3DSC0,
UniProt Related Accession:P43116
Molecular Weight:39,761 Da
NCBI Full Name:Prostaglandin E2 receptor EP2 subtype
NCBI Synonym Full Names:prostaglandin E receptor 2
NCBI Official Symbol:PTGER2
NCBI Official Synonym Symbols:EP2
NCBI Protein Information:prostaglandin E2 receptor EP2 subtype
UniProt Protein Name:Prostaglandin E2 receptor EP2 subtype
UniProt Synonym Protein Names:Prostanoid EP2 receptor
Protein Family:Prostaglandin E2 receptor
UniProt Gene Name:PTGER2
UniProt Entry Name:PE2R2_HUMAN
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Additional Information

Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Cell Biology
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