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Purified Anti-Human IL-4 Antibody [MP4-25D2] (AGEL2380)

Datasheet MSDS
SKU AGEL2380
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Applications ELISA
Reactivity Human
Host Species Rat
Isotype Rat IgG1, κ
Clone MP4-25D2
Conjugation Unconjugated
€25 - €63

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Description

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Purified Anti-Human IL-4 Antibody [MP4-25D2]

The Purified Anti-Human IL-4 Antibody (MP4-25D2) from Assay Genie is a specialized tool designed for researchers studying interleukin-4 (IL-4), a key cytokine involved in immune responses and inflammation regulation. This antibody, developed and validated for use in various research applications, specifically targets the human IL-4 protein, allowing for precise detection and analysis in experimental settings.IL-4, known for its roles in coordinating immune responses and influencing the differentiation of T-helper cells, plays a crucial part in various physiological and pathological processes. By utilizing the Purified Anti-Human IL-4 Antibody (MP4-25D2), researchers can gain deeper insights into the functions of IL-4 in immunology, allergy research, and studies related to inflammatory diseases.

The high specificity and reactivity of this antibody with human samples make it a reliable tool for investigations seeking to understand the intricate mechanisms of IL-4-mediated immune modulation.With its potential applications in a wide range of research areas, including allergy, autoimmune disorders, and infectious diseases, the Purified Anti-Human IL-4 Antibody (MP4-25D2) offers a valuable resource for scientists looking to unravel the complexities of IL-4 signaling pathways and its impact on immune system regulation. By utilizing this antibody, researchers can enhance their studies and contribute to advancements in the field of immunological research.

Product Title:Purified Anti-Human IL-4 Antibody [MP4-25D2]
SKU:AGEL2380
Size:25µg, 100µg
Clone No:MP4-25D2
Synonyms:Interleukin-4;IL-4;B-cell IgG differentiation factor;B-cell growth factor 1;BSF-1;IGG1 induction factor;
Host Species:Rat
Reactivity:Human
Application:ICFCM;ELISA
Isotype:Rat IgG1, κ
Isotype Control:Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by ELISA assay. Purified MP4-25D2 has been tested by blocking fluorochrome conjugated MP4-25D2 for intracellular cytokine staining. In order to obtain complete blocking results, a saturated amount of purified antibody (≤ 5.0 µg/million cells) should be used for incubation with target cells, prior to staining with fluorochrome conjugated antibody. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05112
Gene ID:3565
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
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