The PE GenieFluor 594 Anti-Human IL-4 Antibody (MP4-25D2) is a specialized antibody designed for the detection of Interleukin-4 (IL-4), a key cytokine involved in the regulation of immune responses. This antibody is raised against human IL-4, ensuring high reactivity and specificity for human samples. Validated for use in a variety of applications, including flow cytometry and immunofluorescence, this antibody specifically targets IL-4, enabling precise detection and analysis in different cell types.IL-4 is a critical signaling molecule that plays a pivotal role in the regulation of immune responses, including the differentiation of T helper cells and the promotion of allergic reactions.
By targeting IL-4, researchers can gain valuable insights into the mechanisms underlying immune regulation, inflammation, and allergic responses. The PE GenieFluor 594 Anti-Human IL-4 Antibody is an essential tool for studies in immunology, allergy research, and the development of potential therapies targeting IL-4-mediated pathways in diseases such as asthma, allergies, and autoimmune disorders.
PE/Genie Fluor 594 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05112
Gene ID:
3565
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
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