Anti-RAB10 Antibody (CAB4459)
- SKU:
- CAB4459
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RAB10
- Research Area:
- Cell Biology
Description
| Product Name: | RAB10 Rabbit pAb |
| Product Code: | CAB4459 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | RAB10 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RAB10 (NP_057215.3). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RAB10 (NP_057215.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAKK TYDL LFKL LLIG DSGV GKTC VLFR FSDD AFNT TFIS TIGI DFKI KTVE LQGK KIKL QIWD TAGQ ERFH TITT SYYR GAMG IMLV YDIT NGKS FENI SKWL RNID EHAN EDVE RMLL GNKC DMDD KRVV PKGK GEQI AREH GIRF FETS AKAN INIE KAFL TLAE DILR KTPV KEPN SENV DISS GG |
| Gene ID: | 10890 |
| Uniprot: | P61026 |
| Cellular Location: | Cell projection, Cytoplasmic side, Cytoplasmic vesicle, Cytoplasmic vesicle membrane, Endoplasmic reticulum membrane, Endosome membrane, Golgi apparatus, Lipid-anchor, Recycling endosome membrane, cilium, phagosome membrane, trans-Golgi network membrane |
| Calculated MW: | 22kDa |
| Observed MW: | 22kDa |
| UniProt Protein Function: | RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor. |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: Golgi apparatus; phagocytic vesicle membrane; endoplasmic reticulum membrane; recycling endosome; cytoplasmic vesicle membrane; focal adhesion; recycling endosome membrane; exocyst; plasma membrane; endosome membrane; trans-Golgi network; endosome Molecular Function:GTPase activity; GDP binding; GTP binding; myosin V binding Biological Process: metabolic process; establishment of neuroblast polarity; protein secretion; endosome transport; regulation of exocytosis; vesicle-mediated transport; polarized epithelial cell differentiation; intracellular protein transport; Golgi to plasma membrane transport; antigen processing and presentation; cellular response to insulin stimulus; axonogenesis; Golgi to plasma membrane protein transport; Rab protein signal transduction; vesicle docking during exocytosis |
| NCBI Summary: | RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009] |
| UniProt Code: | P61026 |
| NCBI GenInfo Identifier: | 46577638 |
| NCBI Gene ID: | 10890 |
| NCBI Accession: | P61026.1 |
| UniProt Related Accession: | P61026 |
| Molecular Weight: | 22.5kDa |
| NCBI Full Name: | Ras-related protein Rab-10 |
| NCBI Synonym Full Names: | RAB10, member RAS oncogene family |
| NCBI Official Symbol: | RAB10Â Â |
| NCBI Protein Information: | ras-related protein Rab-10 |
| UniProt Protein Name: | Ras-related protein Rab-10 |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB10Â Â |
| UniProt Entry Name: | RAB10_HUMAN |
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