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Rat C1QBP Recombinant Protein (N-His)
Key Features

Rat C1QBP Recombinant Protein (N-His) (GXRP06164)

SKU GXRP06164
Product Type Recombinant Protein
Species Rat
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Rat C1QBP Recombinant Protein (N-His)

Rat C1QBP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu72-Gln279, with an N-terminal His tag. Predicted molecular weight: 26.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) is a ~30 kDa protein. Multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. For research use only.

At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular 'heads' of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation.

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