Description
Recombinant Amyloid-β Monoclonal Antibody
The Recombinant Amyloid-β Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110510) against Amyloid-β. This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind toThe acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others formThe protein basis ofThe amyloid plaques found inThe brains of patients with Alzheimer disease. In addition, two ofThe peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of SH-SY5Y. The target is localized to the membrane.
| Product Name: | Recombinant Amyloid-β Monoclonal Antibody |
| SKU: | AGEL5824 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | A4, A4 amyloid protein, AAA, ABETA, Abeta 40, ABPP, AD1, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Alzheimer disease amyloid protein, Amyloid beta (A4) precursor protein, amyloid beta 40, Amyloid Beta 42, Amyloid beta A, Amyloid beta A4, Amyloid beta A4 protein, Amyloid beta precursor protein, Amyloid beta protein, Amyloid intracellular domain 50, Amyloid intracellular domain 57, Amyloid intracellular domain 59, Amyloid Precursor, Amyloid Precursor Protein, Amyloid Precursor Protein 695, APP, APP A4 AD, APP A4 AD1, APP695, APPI, Aβ(1-40), Aβ(1-42), Aβ40, Aβ42, Beta amyloid peptide, Beta-amyloid precursor protein, Beta-amyloid protein, Beta-amyloid protein 40, Beta-APP40, Beta-APP42, C31, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), peptidase nexin II, PN 2, PN II, PN-II, PN2, preA, preA4, Protease nexin II, Protease nexin-II, S-APP-alpha, S-APP-beta, Soluble APP-beta |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Amyloid-β protein |
| Applications: | WBIHCIFIPELISA |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C110510 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | Amyloid-β |
| Conjugation: | Unconjugated |
| Observed MW: | 100 kDa |
| Calculated MW: | 87 kDa |
| Recommended Dilution: | IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200 |
| UniProt: | P05067 |
| Purification: | Protein A |
| Concentration: | 0.2 mg/mL |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |
