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Key Features

Recombinant APAF1 Monoclonal Antibody (AGEL6915)

Datasheet MSDS
SKU AGEL6915
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IP
Host Species Rabbit
Clonality Monoclonal
Clone C131610
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant APAF1 Monoclonal Antibody

The Recombinant APAF1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131610) against APAF1. Apoptotic protease activating factor 1 (Apaf-1), originally identified as the mammalian homolog of the C. elegans apoptotic regulatory protein CED-4, is an important signaling protein involved in the activation of caspase-9 during apoptosis. Cytosolic Apaf-1 forms a complex with caspase-9 in the presence of cytochrome c and dATP, ultimately leading to caspase-9 activation and subsequent activation of caspase-3. The protein contains an amino-terminal CARD domain, a central CED-4 homology domain, and multiple WD-40 repeats at the carboxy terminus. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IP applications. It has been validated by WB analysis of 293. The target is localized to the cytoplasm.

Product Name:Recombinant APAF1 Monoclonal Antibody
SKU:AGEL6915
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:APAF, APAF 1, APAF-1, APAF1, Apoptotic peptidase activating factor, Apoptotic peptidase activating factor 1, Apoptotic protease activating factor, Apoptotic protease activating factor 1, Apoptotic protease-activating factor, Apoptotic protease-activating factor 1, CED, CED 4, CED4, KIAA, KIAA0413
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein of human APAF1
Applications:WBIP
Clonality:Recombinant Monoclonal
Clone No:C131610
Host:Rabbit
Isotype:Rabbit IgG
Target:APAF1
Conjugation:Unconjugated
Observed MW:142 kDa
Calculated MW:142 kDa
Recommended Dilution:WB 1:1000; IP 1:20-50
UniProt:O14727
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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