The Recombinant ATF6A Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110717) against ATF6A. This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of A549. The target is localized to the cytoplasm.
Product Name:
Recombinant ATF6A Monoclonal Antibody
SKU:
AGEL6025
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ACHM, ACHM7, ATF, ATF6, ATF6A
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human ATF6A protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110717
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ATF6A
Conjugation:
Unconjugated
Observed MW:
100 kDa
Calculated MW:
75 kDa
Recommended Dilution:
WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P18850
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
