The Recombinant Hamartin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C431674) against Hamartin. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that causes symptoms including hamartomas in brain, kidney, heart, lung and skin. The tumor suppressor genes TSC1 and TSC2 encode hamartin and tuberin, respectively. Hamartin and tuberin form a functional complex and are involved in numerous cellular activities such as vesicular trafficking, regulation of the G1 phase of the cell cycle, steroid hormone regulation, Rho activation and anchoring neuronal intermediate filaments to the actin cytoskeleton. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of Mouse brain, PC-12. The target is localized to the cytoplasm.
Product Name:
Recombinant Hamartin Monoclonal Antibody
SKU:
AGEL6979
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
hamartin, KIAA, KIAA0243, LAM, TSC, TSC1
Reactivity:
Mouse, Rat
Immunogen:
Peptide. This information is proprietary to PTMab.
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C431674
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Hamartin
Conjugation:
Unconjugated
Observed MW:
160 kDa
Calculated MW:
130 kDa
Recommended Dilution:
WB 1:1000
UniProt:
Q92574
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
![Anti-Hamartin [R06-2S5] Monoclonal Antibody (AGMB00484)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271773/691875/anti-hamartin-r06-2s5-monoclonal-antibody-agmb00484__65923.1774504397.jpg?c=2 "Anti-Hamartin [R06-2S5] Monoclonal Antibody (AGMB00484)")
