The Recombinant BMP-2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110049) against BMP2. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of LNCaP, Hela, HepG2, Raw264.7, Rat spleen, Rat lung, Rat testis, IHC analysis of Mouse liver and IF analysis of HEK293. The target is localized to the secreted.
Product Name:
Recombinant BMP-2 Monoclonal Antibody
SKU:
AGEL5368
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
BDA, BDA2, BDA2A, BMP, BMP-2, BMP-2A, BMP2, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human / Mouse / Rat / Rhesus / Canine BMP-2 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110049
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
BMP2
Conjugation:
Unconjugated
Observed MW:
30 kDa, 13 kDa
Calculated MW:
45 kDa, 13 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P12643, P21274, P49001
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
0.2 µm filtered solution in PBS
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.