The Recombinant BNI3L Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110746) against BNI3L. This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of MCF7. The target is localized to the Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane, single-pass membrane protein, Colocalizes with SPATA18 at the mitochondrion outer membrane.
Product Name:
Recombinant BNI3L Monoclonal Antibody
SKU:
AGEL6054
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Adenovirus E1B19k binding protein B5, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kd protein interacting protein 3a, BCL2/adenovirus E1B 19 kDa protein interacting protein 3A, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, BCL2/adenovirus E1B 19kDa interacting protein 3 like, BNI3L, BNIP3a, BNIP3H, BNIP3L, BNIP3L protein, NIP3 like protein X, NIP3-like protein X, NIP3L, NIX
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human BNI3L protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110746
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
BNI3L
Conjugation:
Unconjugated
Observed MW:
38 kDa
Calculated MW:
24 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:500-2000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
O60238
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant BNI3L Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: MCF7 lysate. Observed-MW:38 kDa Calculated-MW:24 kDa