The Recombinant BSND Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C120856) against BSND. This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Mouse spleen. The target is localized to the Basolateral cell membrane {ECO:0000269|PubMed:18776122}; Multi-pass membrane protein {ECO:0000255}. Note: Mostly sorted at the basolateral membrane. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.
Product Name:
Recombinant BSND Monoclonal Antibody
SKU:
AGEL6162
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
BART, barttin, BSND, DFNB, DFNB73
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human BSND protein
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C120856
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
BSND
Conjugation:
Unconjugated
Observed MW:
35 kDa
Calculated MW:
35 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000
UniProt:
Q8WZ55
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
