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Recombinant c-Kit Monoclonal Antibody (AGEL6420)

Datasheet MSDS
SKU AGEL6420
Product Type Antibody
Reactivity Human
Applications IHC
Host Species Rabbit
Clonality Monoclonal
Clone C351114
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant c-Kit Monoclonal Antibody

The Recombinant c-Kit Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C351114) against c-Kit. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for IHC applications. It has been validated by IHC analysis of Human seminoma. The target is localized to the cytoplasm, membrane.

Product Name:Recombinant c-Kit Monoclonal Antibody
SKU:AGEL6420
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:C Kit, C-Kit, c-Kit Ligand, CD117, CD_antigen: CD117, KIT, Kit Ligand, KIT oncogene, KIT proto oncogene receptor tyrosine kinase, KIT proto-oncogene receptor tyrosine kinase, Mast cell growth factor receptor, Mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, soluble KIT variant 1, Steel Factor Receptor, Stem cell factor receptor, tyrosine protein kinase Kit, Tyrosine-protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Reactivity:Human
Immunogen:Recombinant human c-Kit fragment
Applications:IHC
Clonality:Recombinant Monoclonal
Clone No:C351114
Host:Rabbit
Isotype:Rabbit IgG
Target:c-Kit
Conjugation:Unconjugated
Recommended Dilution:IHC 1:200-1000
UniProt:P10721
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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