The Recombinant Caspase 8 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C033326) against Caspase 8. Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Hamster samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of CHO-K1. The target is localized to the cytoplasm.