The Recombinant CD3E Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C531614) against CD3E. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery. This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε, and δ. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Mouse samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of EL4.IL2, Mouse thymus. The target is localized to the membrane.
