The Recombinant CD3e/CD3 epsilon Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110020) against CD3E. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Jurkat, MOLT4, Mouse thymus, Rat thymus, IHC analysis of Human tonsil and IF analysis of Human tonsil, Mouse spleen, Rat spleen. The target is localized to the cell membrane.
