The Recombinant CD40 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321331) against CD40. The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Raji and IHC analysis of Human Hodgkin lymphoma. The target is localized to the cell membrane and secreted.
Product Name:
Recombinant CD40 Monoclonal Antibody
SKU:
AGEL6636
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AI326936, B cell associated molecule CD40, B cell surface antigen CD40, B cell-associated molecule, B-cell surface antigen CD, B-cell surface antigen CD40, Bp50, CD 40, CD40, CD40 (protein), CD40 antigen, CD40 antigen (TNF receptor superfamily member 5), CD40 molecule, CD40 protein, CD40 type II isoform, CD40L receptor, CDW, CDW40, GP39, HIGM1, IGM, IMD3, isoform CRA_a, member 5, MGC9013, Nerve growth factor receptor related B lymphocyte activation molecule, OTTHUMP00000031699, OTTHUMP00000031700, p50, T-BAM, TBAM, TNF receptor superfamily member 5, TNFRSF, TNFRSF5, TNR5, TRAP, Tumor necrosis factor receptor superfamily, Tumor necrosis factor receptor superfamily member, Tumor necrosis factor receptor superfamily member 5, Tumor necrosis factor receptor superfamily member 5 precursor
Reactivity:
Human
Immunogen:
Recombinant human CD40 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C321331
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CD40
Conjugation:
Unconjugated
Observed MW:
44-48 kDa
Calculated MW:
32 kDa
Recommended Dilution:
WB 1:1000-5000; IHC 1:200-1000
UniProt:
P25942
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
