The Recombinant CD47 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C251103) against CD47. Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for IHC and FCM applications. It has been validated by IHC analysis of Human ovarian cancer, Human cerebrum, Human placenta, Mouse cerebrum and FCM analysis of Jurkat, MCF-7. The target is localized to the membrane.
Product Name:
Recombinant CD47 Monoclonal Antibody
SKU:
AGEL6409
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA, Antigenic surface determinant protein OA3, CD 47, CD47, CD47 antigen, CD47 glycoprotein, CD47 molecule, IAP, Integrin Associated Protein, Integrin associated signal transducer, Integrin-associated protein, Integrin-associated protein (IAP), Leukocyte surface antigen CD, Leukocyte surface antigen CD47, MER, MER 6, MER6, OA 3, OA3, OTTHUMP00000041152, OTTHUMP00000041153, Protein MER, Protein MER6, Rh related antigen, Surface antigen identified by monoclonal 1D8
Reactivity:
Human, Mouse
Immunogen:
Recombinant human CD47 fragment
Applications:
IHCFCM
Clonality:
Recombinant Monoclonal
Clone No:
C251103
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CD47
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:200-1000; FCM 1:50-100
UniProt:
Q08722
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
