The Recombinant CD47 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331557) against CD47. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HepG2, Jurkat, 293T, A549, U-2 OS, Molt4, HL-60. The target is localized to the cell membrane.
Product Name:
Recombinant CD47 Monoclonal Antibody
SKU:
AGEL6862
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA, Antigenic surface determinant protein OA3, CD 47, CD47, CD47 antigen, CD47 glycoprotein, CD47 molecule, IAP, Integrin Associated Protein, Integrin associated signal transducer, Integrin-associated protein, Integrin-associated protein (IAP), Leukocyte surface antigen CD, Leukocyte surface antigen CD47, MER, MER 6, MER6, OA 3, OA3, OTTHUMP00000041152, OTTHUMP00000041153, Protein MER, Protein MER6, Rh related antigen, Surface antigen identified by monoclonal 1D8
Reactivity:
Human
Immunogen:
Recombinant human CD47 fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331557
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CD47
Conjugation:
Unconjugated
Observed MW:
47-52 kDa
Calculated MW:
47-52 kDa
Recommended Dilution:
WB 1:1000-2000
UniProt:
Q08722
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
