The Recombinant Cdc42 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111482) against Cdc42. Cdc42, the human homologue of the cell division cycle 42 of Saccharomyces cerevisiae, belongs to the Rho/Rac subfamily of Ras-like GTPases. It acts as molecular switches to regulate numerous cellular responses including the organization of the actin cytoskeleton, gene transcription, cell cycle progression, and membrane trafficking. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of PC-3, Mouse brain, IHC analysis of Mouse colon, Rat colon and IF analysis of PC-3. The target is localized to the cell membrane, cytoskeleton.