The Recombinant Claudin-1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111115) against Claudin-1. Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of HL60, HUVEC, Human CAF, HCT116, A549, Jurkat, HT22, Thp-1, HK-2, PC-12, 3T3-L1, PC-3, U-14, 293F, HepG2, A431, Mouse skin, SNU-1, SNU-668, SNU719, AGS, SW480, SW620, CACO-2, IHC analysis of Mouse stomach, Rat stomach, Human breast, Mouse mammary gland, Human tonsil and IF analysis of A549, Mouse mammary gland. The target is localized to the membrane.
![Anti-Claudin 1 [R06-6C-1] Monoclonal Antibody (AGMB06896)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/278177/732754/anti-claudin-1-r06-6c-1-monoclonal-antibody-agmb06896__95088.1777187846.jpg?c=2 "Anti-Claudin 1 [R06-6C-1] Monoclonal Antibody (AGMB06896)")