The Recombinant Claudin 3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110226) against Claudin 3. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of HT-29. The target is localized to the membranous.
Product Name:
Recombinant Claudin 3 Monoclonal Antibody
SKU:
AGEL5545
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
C7orf, C7orf1, C7orf1 CPETR, C7orf1 CPETR2, Claudin 3, claudin-3, Claudin3, CLD3, CLDN, CLDN 3, CLDN3, Clostridium perfringens enterotoxin receptor 2, CPE R2, CPE receptor 2, CPE-R 2, CPE-R2, CPE-receptor, CPE-receptor 2, CPETR, CPETR 2, CPETR2, HRVP, HRVP 1, HRVP1, Rat ventral prostate 1 like protein, Rat ventral prostate.1 protein homolog, RVP, RVP1, Ventral prostate.1 like protein, Ventral prostate.1 protein homolog
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Claudin 3 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110226
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Claudin 3
Conjugation:
Unconjugated
Observed MW:
20 kDa
Calculated MW:
23 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
O15551
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
