The Recombinant ClC-2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121344) against ClC-2. ClC-2 (chloride channel protein 2) is a transmembrane protein and functions as a voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. ClC-2 is highly expressed in adrenal gland and involved in the regulation of aldosterone production. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, HT-29, Rat kidney, Mouse kidney and IHC analysis of Human testis. The target is localized to the membrane.
