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Recombinant Cleaved PARP1 Monoclonal Antibody (RMEA1004)

Datasheet MSDS
SKU RMEA1004
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C111003
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant Cleaved PARP1 Monoclonal Antibody

The Recombinant Cleaved PARP1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111003) against Cleaved PARP1. This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of RAW264.7. The target is localized to the cytoplasmic, nuclear.

Product Name:Recombinant Cleaved PARP1 Monoclonal Antibody
SKU:RMEA1004
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ADP-ribosyltransferase diphtheria toxin-like, ADP-ribosyltransferase diphtheria toxin-like 1, ADPRT, ADPRT 1, ADPRT1, APOPAIN, ARTD, ARTD1, Cleaved PARP, NAD(+) ADP-ribosyltransferase, NAD(+) ADP-ribosyltransferase 1, pADPRT, pADPRT-1, PARP, PARP-1, PARP1, Poly [ADP-ribose] polymerase, Poly [ADP-ribose] polymerase 1, Poly ADP ribose polymerase, Poly ADP ribose polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) polymerase 1, Poly[ADP-ribose] synthase, Poly[ADP-ribose] synthase 1, PPOL, SCA, SCA1
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human Cleaved PARP1 protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C111003
Host:Rabbit
Isotype:Rabbit IgG
Target:Cleaved PARP1
Conjugation:Unconjugated
Observed MW:25 kDa
Calculated MW:25 kDa
Recommended Dilution:IHC 1:200-1000; WB 1:500-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:P09874
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageWestern Blot with Recombinant Cleaved PARP1 Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: RAW264.7 cell lysate. Observed-MW:25 kDa Calculated-MW:25 kDa
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