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Key Features

Recombinant Cofilin Monoclonal Antibody (AGEL8639)

Datasheet MSDS
SKU AGEL8639
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, IF
Host Species Rabbit
Clonality Monoclonal
Clone C313334
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant Cofilin Monoclonal Antibody

The Recombinant Cofilin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C313334) against Cofilin. Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility, cytokinesis, and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of A549, MCF-7, 293T and IHC analysis of Human lung cancer. The target is localized to the Nucleus matrix. Cytoplasm>cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.

Product Name:Recombinant Cofilin Monoclonal Antibody
SKU:AGEL8639
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:18 kDa phosphoprotein, CFL, CFL 1, CFL1, COF1, Cofilin, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, Cofilin-1, epididymis secretory protein Li 15, HEL-S-15, non-muscle isoform, p18
Reactivity:Human
Immunogen:A synthetic peptide of human Cofilin
Applications:WBIHC-PIF
Clonality:Recombinant Monoclonal
Clone No:C313334
Host:Rabbit
Isotype:Rabbit IgG
Target:Cofilin
Conjugation:Unconjugated
Observed MW:19 kDa
Calculated MW:19 kDa
Recommended Dilution:WB 1:500-1000; IHC 1:50-200; IF 1:50-100
UniProt:P23528
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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