The Recombinant Collagen II Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310958) against Collagen II. This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of A431. The target is localized to the cytoplasmic.
Product Name:
Recombinant Collagen II Monoclonal Antibody
SKU:
AGEL6264
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Alpha 1 type II collagen, Alpha-1 type II collagen, ANFH, AOM, Cartilage collagen, Chondrocalcin, CO2A, CO2A1, COL11A, COL11A3, COL2A, COL2A1, Collagen, Collagen 2, Collagen II, Collagen II alpha 1 polypeptide, collagen type, collagen type 2, CTX2, PIICP, PIINP, SEDC, STL, STL1
Reactivity:
Human
Immunogen:
Recombinant Human Collagen II protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C310958
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Collagen II
Conjugation:
Unconjugated
Observed MW:
200 kDa
Calculated MW:
142 kDa
Recommended Dilution:
IHC 1:100-500; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P02458
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
