The Recombinant Connexin 43 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110974) against Connexin 43. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Rat womb. The target is localized to the membrane.
Product Name:
Recombinant Connexin 43 Monoclonal Antibody
SKU:
AGEL6280
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AVSD, AVSD3, CMDR, Connexin 43, Connexin-43, Cx 43, CX43, CXA1, DFNB38, EKVP, EKVP3, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein, Gap junction protein alpha 1 43kDa, Gap junction protein alpha 1 43kDa (connexin 43), Gap junction protein alpha like, GJA, GJA 1, GJA1, GJAL, HLHS, HLHS1, HSS, ODD, ODDD, ODOD, PPKCA, SDTY3
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Connexin 43 protein
Applications:
WBIHCIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110974
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Connexin 43
Conjugation:
Unconjugated
Observed MW:
43 kDa
Calculated MW:
43 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
P17302
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Western Blot with Recombinant Connexin 43 Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: Rat womb cell lysate. Observed-MW:43 kDa Calculated-MW:43 kDa