The Recombinant DDB2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321541) against DDB2. Damaged DNA-Binding Protein (DDB) consists of a 127 kDa subunit (DDB-1) and a 48 kDa subunit (DDB-2) that contribute to the formation of the UV-damaged DNA-binding protein complex (UV-DDB). In conjunction with CUL4A and ROC-1, the UV-DDB complex forms an E3 ubiquitin ligase that recognizes a broad spectrum of DNA lesions such as cyclobutane pyrimidine dimers, 6-4 photoproducts, apurinic sites and short mismatches. The complex polyubiquitinates components of the nucleotide excision repair pathway. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Raji. The target is localized to the nucleus.
Product Name:
Recombinant DDB2 Monoclonal Antibody
SKU:
AGEL6846
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
DDB, DDB2, DDBB, UV-DDB, UV-DDB2, XPE
Reactivity:
Human
Immunogen:
A synthetic peptide of human DDB2
Applications:
WBIHC-P
Clonality:
Recombinant Monoclonal
Clone No:
C321541
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
DDB2
Conjugation:
Unconjugated
Observed MW:
48 kDa
Calculated MW:
48 kDa
Recommended Dilution:
WB 1:1000-5000; IHC-P 1:500-2000
UniProt:
Q92466
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
![Anti-DDB2 [R09-1D5] Monoclonal Antibody (AGMB00491)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/271780/691551/anti-ddb2-r09-1d5-monoclonal-antibody-agmb00491__05075.1774503332.jpg?c=2 "Anti-DDB2 [R09-1D5] Monoclonal Antibody (AGMB00491)")
