The Recombinant Dnmt1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110462) against DNMT1. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Jurkat. The target is localized to the nucleus.
Product Name:
Recombinant Dnmt1 Monoclonal Antibody
SKU:
AGEL5779
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ADCADN, AIM, CXXC, CXXC finger protein 9, CXXC finger protein 9|DNA methyltransferase, CXXC finger protein 9|DNA methyltransferase 1, CXXC-type zinc finger protein 9, CXXC9, DNA (cytosine 5) methyltransferase 1, DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA methyltransferase M. HsaI., DNA MTase, DNA MTase HsaI, DNMT, DNMT 1, DNMT1, Dnmt1o, FLJ16293, HSN1E, m. HsaI, MCMT, Met1, MGC, MGC104992, mMmul, MommeD2
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human Dnmt1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110462
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
DNMT1
Conjugation:
Unconjugated
Observed MW:
183 kDa
Calculated MW:
183 kDa
Recommended Dilution:
IHC 1:1000-4000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P26358
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.