The Recombinant DNMT1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311350) against DNMT1. Dnmt1 is an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF and IP applications. It has been validated by WB analysis of Jurkat, IHC analysis of Human stomach, Human tonsil, IF analysis of HeLa and IP analysis of Jurkat cells extracts. The target is localized to the nucleus.
Product Name:
Recombinant DNMT1 Monoclonal Antibody
SKU:
AGEL6655
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
ADCADN, AIM, CXXC, CXXC finger protein 9, CXXC finger protein 9|DNA methyltransferase, CXXC finger protein 9|DNA methyltransferase 1, CXXC-type zinc finger protein 9, CXXC9, DNA (cytosine 5) methyltransferase 1, DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA methyltransferase M. HsaI., DNA MTase, DNA MTase HsaI, DNMT, DNMT 1, DNMT1, Dnmt1o, FLJ16293, HSN1E, m. HsaI, MCMT, Met1, MGC, MGC104992, mMmul, MommeD2
Reactivity:
Human
Immunogen:
Recombinant human Dnmt1 fragment
Applications:
WBIHCIFIP
Clonality:
Recombinant Monoclonal
Clone No:
C311350
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
DNMT1
Conjugation:
Unconjugated
Observed MW:
200 kDa
Calculated MW:
183 kDa
Recommended Dilution:
WB 1:500-1000; IHC 1:200-1000; IF 1:50; IP 1:25-50
UniProt:
P26358
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.