The Recombinant ELP4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111392) against ELP4. Elongator Acetyltransferase Complex Subunit 4 (ELP4) is a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. The elongator complex catalyzes formation of carboxy methyluridine in the wobble base at position 34 in tRNAs. Diseases associated with ELP4 include Aniridia 2 and Coloboma of Optic Nerve. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P and ICC/IF applications. It has been validated by WB analysis of 3T3 and IF analysis of 3T3. The target is localized to the cell nucleus and cytosol.
Product Name:
Recombinant ELP4 Monoclonal Antibody
SKU:
AGEL6697
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
C11orf, C11orf19, dJ68P15A, dJ68P15A.1, Elongation protein 4 homolog, elongation protein 4 homolog (S. cerevisiae), Elongator complex protein, Elongator complex protein 4, ELP, ELP4, FLJ20498, hELP, hELP4, PAX6 neighbor gene protein, PAX6NEB, PAXNEB
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of Human ELP4
Applications:
WBIHC-PICC/IF
Clonality:
Recombinant Monoclonal
Clone No:
C111392
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ELP4
Conjugation:
Unconjugated
Observed MW:
47 kDa
Calculated MW:
47 kDa
Recommended Dilution:
WB 1:1000; IHC-P 1:200-500; ICC/IF 1:100-200
UniProt:
Q96EB1
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.