The Recombinant EPHB4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C221138) against EPHB4. EPHB4 together with its cognate ligand/functional ligand EFNB2 they are involved in the regulation of cell adhesion and migration, and play a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of HeLa, Rat spleen and IHC analysis of Human breast. The target is localized to the membrane.
Product Name:
Recombinant EPHB4 Monoclonal Antibody
SKU:
AGEL6444
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
EPHB, EPHB4, HFASD, HTK, MYK, MYK1, TYRO, TYRO11
Reactivity:
Human, Mouse
Immunogen:
Recombinant protein of human Eph receptor B4/HTK
Applications:
WBIHC-P
Clonality:
Recombinant Monoclonal
Clone No:
C221138
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
EPHB4
Conjugation:
Unconjugated
Observed MW:
135 kDa
Calculated MW:
108 kDa
Recommended Dilution:
WB 1:1000; IHC-P 1:200-1000
UniProt:
P54760
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
